Science Meets Beauty. BioPlus USA Redefines Regenerative Skincare.
Powered by Korean biotechnology and advanced growth-factor science, BioPlus USA delivers next-generation skin and scalp rejuvenation solutions designed for medical professionals.

About BioPlus USA
Founded on over three decades of biotechnology research, BioPlus USA represents the evolution of science-based aesthetics.
Our mission is to bridge the gap between biomedical innovation and clinical beauty, offering medical spas, clinics, and professionals access to HUGRO™ — a breakthrough recombinant growth-factor technology that supports true cellular recovery, rejuvenation, and longevity.
Through our U.S. headquarters, we bring the precision of Korean biotech to practitioners across America — empowering them with clinically proven, high-performance products designed for advanced skin, scalp, and anti-aging treatments.
Our Technology – Hugro® Peptide
HUGRO is the original cell booster engineered by recombining growth factors using cutting-edge genetic technology.
The First Topical Cell Booster


Recombinant Growth Factor Engineering
replicates human growth factors with clinical-grade stability.
AUT (Anti-Ubiquitination Technology)
extends protein lifespan by preventing degradation, ensuring sustained activity within the skin.
BMTS (Bio-Material Transdermal System)
enhances skin permeability, enabling growth factors to penetrate deep into the dermis without invasive procedures.
Together, these technologies create a cell-penetrating delivery system that transforms the way skin regenerates — repairing, restoring, and revitalizing from within.
Our Products
Advanced Skin & Scalp Boosters for Professional Use.
Shine Plus Aura
A medical-grade skin booster designed for microneedling treatments.
Formulated with 18 recombinant growth factors powered by HUGRO™ technology, it delivers hydration, firmness, and radiance through deep dermal penetration. Ideal for improving texture, elasticity, and fine lines.
Hair LC Aura Hair
A scalp-rejuvenation booster that nourishes follicles and revitalizes weak scalp tissue.
Combining AUT and BMTS delivery systems, it reduces redness by 45% and promotes healthy hair growth with clinically proven results.
Bonyx (LC Rebo)
A high-end aesthetic line formulated with Light Chain BTX and growth-factor peptides.
This series focuses on anti-aging, wrinkle reduction, and dermal restoration — representing the pinnacle of luxury medical aesthetics.
Clinical Results
Visible Transformation. Proven by Science.


+30% increase in skin density after 8 weeks
This clinical result comes from Shine Plus Aura, showing a 30% improvement in skin density after eight weeks of professional microneedling treatment.


+44% improvement in dermal tissue elasticity
This outcome is from the Bonyx line, demonstrating a 44% increase in dermal elasticity in users following regular topical application.


45% reduction in scalp redness
This result is associated with Hair LC Aura Hair, showing a 45% decrease in scalp redness and a noticeable soothing effect after treatment.
Join the Future of Regenerative Aesthetics.
Experience the next era of biotechnology-driven skincare.
Partner with BioPlus USA to bring HUGRO™-powered innovations to your clinic or distribution network.